Vitamin B6 in its active form
• Helps in tissue formation
• Helps the body metabolize carbohydrates, fats and proteins
• Helps to prevent vitamin B6 deficiency
• Provides 20 mg of vitamin B6 per daily dose
KEY INGREDIENTS: Brain, Eleuthero Root, Ginkgo Leaf, Vitamin B6
TPIN is a source of vitamin B6 in the form of pyridoxal-5-phosphate (PLP). As the most biologically active form of the vitamin, PLP helps to catalyze over 140 reactions.1 Vitamin B6 participates in nearly all metabolic reactions involving amino acids, including their synthesis and breakdown.1Approximately 70-80% of vitamin B6 is present in muscle, where it acts as a coenzyme for glycogen phosphorylase.1 This enzyme is necessary for glycogenolysis, which breaks down glycogen into glucose and provides fuel to muscle during exercise.1 Low levels of vitamin B6 also lead to increased synovial fluid between joints, which results in nerve compression.2 Eleuthero root is a thorny shrub native to Siberia and northern parts of China, and its beneficial health effects arise from the high levels of lignans in its roots.3 TPIN also contains an extract from Ginkgo biloba, an ancient plant traditionally used in Chinese medicine.4 Ginkgo contains flavonoids, terpenoids and proanthocyanidins, which are responsible for its positive health effects.4
1. Mooney, S, Leuendorf, JE, Hendrickson, C, Hellmann, H. Molecules. 2009; 14: 329-351.
2. Combs, GF. (2012). In The Vitamins (4th ed., pp. 309-323). Elsevier.
3. Murthy, HN, Kim, YS, Georgiev, MI, Paek, KY. Appl Microbiol Biotechnol. 2014; 98: 7319-7329.
4. Brondino, N, De Silvestri, A, Re, S, Lanati, N, Thiemann, P, Verna, A, Emanuele, E, Politi, P. Evidence-Based Complementary and Alternative Medicine. 2013; 2013: 915691.